http://dspace.lamu.edu.zm:8080/handle/123456789/2889 2026-10-13T05:27:23Z 2026-10-13T05:27:23Z Safa, Ashrafus Sultana, Jinath Cam, Dac Phung Mwansa, L James Kong, Richard Y.C http://dspace.lamu.edu.zm:8080/handle/123456789/2916 2024-07-18T09:43:57Z 2008-05-14T00:00:00Z

Title: Vibrio cholerae O1 Hybrid El Tor Strains, Asia and Africa Authors: Safa, Ashrafus; Sultana, Jinath; Cam, Dac Phung; Mwansa, L James; Kong, Richard Y.C Abstract: Vibrio cholerae is a water-borne pathogen that causes a severe watery diarrhea disease known as cholera. On the basis of variable somatic O antigen composition, >200 serogroups of V. cholerae have been recognized. Classical and El Tor are 2 well-established biotypes within the V. cholerae O1 serogroup, and they can be distinguished by differences in their biochemical reactions or phenotypic traits (1) Description: This is an article on Vibrio cholerae O1 Hybrid El Tor Strains, Asia and Africa and can be found online using the site doi: 10.3201/eid1406.080129

2008-05-14T00:00:00Z Loti, Patrick Nyirenda, S Stanley Chisulo, K Frank Chama, Agness Singogo, Majory Chileshe, B Daniel Mwansa, L James http://dspace.lamu.edu.zm:8080/handle/123456789/2915 2024-07-18T09:26:21Z 2024-05-16T00:00:00Z

Title: Investigation of Malaria Parasitemia among Asymptomatic Individuals in Designated Districts of Central and Muchinga Provinces of Zambia – A Cross Sectional Study Authors: Loti, Patrick; Nyirenda, S Stanley; Chisulo, K Frank; Chama, Agness; Singogo, Majory; Chileshe, B Daniel; Mwansa, L James Abstract: The aim of the study was to investigate asymptomatic malaria in health-conscious population across four selected districts. Malaria is a life-threatening disease caused by Plasmodium spp. transmitted through bites of infected female Anopheles mosquitoes. Asymptomatic malaria refers to the presence of malaria parasites in vivo without symptoms, which usually provides a reservoir for the disease transmission. Materials and methods. Blood collected in EDTA underwent testing through RDT (SD Bioline one-step malaria antigen P.f. (HRP-II) rapid test kits), while thin and thick blood smears Giemsa stained were microscopically examined. Results and discussion. Out of 385 individuals examined,84 people (21.8 %) tested positive for malaria using RDT and 101/385 (26.2 %) – through microscopy. Microscopic examination further identified 27 individuals (7.0 %) with gametocytes and 74 (19.2 %) – with trophozoites. Intriguingly, 17 (4.4 %) samples showed negative results in RDT but exhibited trophozoites and gametocytes upon smear examination. District-wise analysis demonstrated the highest malaria positivity rate in Kanchibiya district, with 32 cases (8.3 %) detected by RDT and 35 (8.5 %) – through microscopy. Chitambo district followed closely: with RDT and microscopy values of 25 (6.5 %) and 33 (8.4 %), respectively; while Mpika and Serenje districts had 13 (3.4 %) and 14 (3.6 %) prevalence,respectively, with RDT and microscopy at 12 (3.1 %) in both districts [x2=16.3, p-value=0.0118]. The study also revealed that 365/385 (95 %) of the participants demonstrated knowledge and positive attitudes toward malaria. Our findings accentuate the presence of asymptomatic malaria, encompassing trophozoites and gametocytes, among seemingly healthy individuals which poses a health risk to the community. Therefore, it is imperative to implement preventive chemotherapy and strengthen vector control efforts against malaria in order to reduce the infection rate. Description: This is a journal article on the Investigation of Malaria Parasitemia among Asymptomatic Individuals in Designated Districts of Central and Muchinga Provinces of Zambia – A Cross Sectional Study and can be found online using the link DOI: 10.21055/0370-1069-2024-2-188-192

2024-05-16T00:00:00Z