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http://dspace.lamu.edu.zm:8080/handle/123456789/188| Title: | Piperolein B, isopiperolein B and piperamide C9:1(8E): total synthesis and cytotoxicities |
| Authors: | Kayamba, Francis Dunnill, Christopher Hamnett, David J. Rodriguez, Arantxa Georgopoulos, Nikolaos T. Moran, Wesley J. |
| Keywords: | Piper compounds cytotoxic |
| Issue Date: | 2013 |
| Publisher: | The Royal Society of Chemistry |
| Abstract: | Total syntheses of the reported structures of piperolein B, isopiperolein B and piperamide C9:1(8E) have been achieved. The analytical data reported for piperolein B and piperamide C9:1(8E) match the synthetic values, however those for isopiperolein B do not. The cytotoxicities of these three structurally similar compounds against cancer cell lines of different tissue origins were evaluated and the results indicated that these compounds show differential effects on cancer cell viability. |
| Description: | This research article can also be accessed through DOI:10.1039/c3ra42060d |
| URI: | DOI: 10.1039/c3ra42060d http://155.0.177.102:8080/jspui//xmlui/handle/123456789/188 |
| Appears in Collections: | Pharmaceutical Chemistry and Pharmacognosy |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| f. kayamba.pdf | Kayamba Francis | 614.71 kB | Adobe PDF | View/Open |
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